克鲁兹博士（乔昆姆·德·阿尔梅达 饰）一直致力于研究阿兹海默症并获得了一些的成效，这一切源于他的母亲（Dora Elvira Pascual 饰）本身就患有该病，然而克鲁兹研究的结果并没有完全把母亲的病治好，短暂性失忆让母亲经常把克鲁兹刚说过的话很快就忘记了。有一次，克鲁兹带着自己的研究去某个城市做演讲。在这里，他遇到了同样患有阿兹海默症的女歌手Una Vida（安洁纽·艾莉丝 饰），起初他被Una Vida的歌声所吸引，后来才了解到Una Vida的身体状况。克鲁兹想继续帮助Una Vida，希望她可以恢复健康。

《生命伊始》：男主人公本遇到艾娃的时候是7岁，两人在马路上相遇，他们一见钟情，这对金童玉女幸福地生活在一起，度过着生命中的春夏秋冬，然而一场悲剧将他们原本平静美满的生活置于危险之中。艾娃突然被确诊患有癌症，在化疗的漫漫长路中，本一直陪伴在她身边，为她鼓气，甚至在艾娃头发全部掉光后，本也剃掉了所有头发陪她。他们的爱情在突如其来的绝症面前坚贞不渝，非常感人。

Diz (Joel Courtney) is a reckless teenage drifter living life on the run. Abandoned by his parents as a child, he looks out for himself and doesn't accept handouts. He takes whatever he wants and runs. Jaded and determined to answer to no one, Diz lives a life marked by thievery and abandonment. Things change for Diz when he floats into a small town on the Snake River. There he is confronted by an unflappable old man named Marty and falls for Marty's guarded granddaughter, Selah. When Diz robs a local drug-dealing crazy, he becomes the owner of a giant pile of cash and the target of two vicious killers. With more money than he knows what to do with, and criminals at his heels, Diz puts the people he's learned to care about in danger, still trying to win Selah. But some things can't be stolen or bought. The River Thief is a film about guilt, self-sacrifice, and accepting life as a gift.

两个演员，他们最初在拍摄期间，第一次体会到了爱情的滋味，但是当他们在一起后最终争吵结束。爱情的奇妙永远无法捉摸，命运安排他们再次相遇，这个时候的两个人已经都上了年纪。他们要怎么看待彼此呢？

效率专家Joy Miles的自由奔放的婆婆Loraine从路易斯维尔搬到萨凡纳，原本计划到分钟的专家因为错过了航班的时间变成了一辈子因此而改变的爆笑故事旅程。